| Chemical |
Trimethylamine |
| CAS-number : |
75-50-3 |
| |
| Synonyms : |
| N,N,dimethylmethaneamine |
| N-trimethylamine |
| Trimethylamine |
| |
| Sumformula of the chemical : |
| C3H9N |
| EINECS-number : |
| 2008750 |
| |
| State and appearance : |
Colorless gas.
|
| |
| Odor : |
Pungent, fishy, ammoniacal
|
| |
| Molecular weight : |
59.1 |
| |
| Conversion factor, 1 ppm in air=_mg/m3 : |
| 2.45 |
OVA 1999 |
| |
| Conversion factor, 1 mg/m3 in air=_ppm : |
| 0.41 |
OVA 1999 |
| |
| Vapor pressure, mmHg : |
| 1610 |
at 25 °C, HSDB 1998 |
| |
| Water solubility, mg/l : |
| 410000 |
MITI 1992 |
| |
| Melting point, °C : |
| -117 |
MITI 1992 |
| |
-- |
| -2 |
45 % aqueous solution |
| 6 |
25 % aqueous solution |
| |
OVA 1999 |
| |
| Boiling point, °C : |
| 2.9 |
MITI 1992 |
| |
-- |
| 30 |
45 % aqueous solution |
| 43 |
25 % aqueous solution |
| |
OVA 1999 |
| |
| pH : |
| 13 |
45 % aqueous solution |
| |
| pKa : |
| 9.81 |
HSDB 1998 |
| |
| pKb : |
| 4.22 |
HSDB 1998 |
| |
| Log octanol/water coefficient, log Pow : |
| 0.16 |
HSDB 1998 |
| 0.04 |
LOGKOW 1994 |
| |
| Henry's law constant, Pa x m3/mol : |
| 15 |
at 20 °C, HSDB 1998 |
| |
| Volatilization : |
Henry's Law constant fot trimethylamine has been measured to be
1.4x10-4 atm cm3/mol at 25 °C.
Based on this value the
volatilization half-life of trimethylamine from a model river 1
m deep, flowing 1 m/sec has been estimated to be 11 hours (HSDB
1998).
|
| |
| Adsorption/desorption : |
Soil adsorption coefficients Koc of 4 and 29 were estimated for
trimethylamine based on a water solubility of 4.1X10+5 mg/l and
a log Kow of 0.16 (HSDB 1998).
|
| |
| Mobility : |
The low Koc (estimated) values suggest that trimethylamine
would not adsorp significantly to suspended solids and
sediments in water and would be highly mobile in soil.
However
trimethylamine is a bese (pKa 9.81) and sould exist primarily
as a cation under environmental conditions (pH 5 - 9).
As a
result trimethylamine may have greater adsorption and less
mobility than its estimated Koc values indicates (HSDB 1998).
|
| |
| Photochemical degradation in air : |
Trimethylamine sould exist almost entirely in the vapor phase
in the atmosphere.
Reaction with photochemically generated
hydroxyl radicals (conc. 8.0X10+5 mol/cm3) is expected to be
the dominant removal mechanism (half-life appr. 4 hours) (HSDB
1998).
|
| |
| Total degradation in soil : |
If released to moist soil, trimethylamine would be suscptible
to biodegradation.
Potential biodegradation products include
dimethylamine, formaldehyde, formate and carbon dioxide under
aerobic conditions and dimethylamine, ammonia and methane under
anaerobic conditions (HAZARDTEXT 1998).
|
| |
| Total degradation in water : |
Biodegradation:
92% by BOD (NH3)
66% by BOD (NO2)
period: 14d
substance: 100 mg/l
sludge: 30 mg/l
(MITI 1992)
Numerous strains of bacteria isolated from seawater, lake
water, mud, garden soil and activated sludge have been found
capable of growth on trimethylamine. 77.2 % BODT uptake was
observed when trimethylamine was incubated in activated sludge
13 days (HSDB 1998).
|
| |
| Ready biodegradability : |
Confirmed to be biodegradable (Anon. 1987). |
| |
| Other information of bioaccumulation : |
A bioconcentration factor (BCF) of <1 was estimated for
trimethylamine using linear regression equation based of a log
Kow of 0.16.
This BCF value and the high water solubility of
trimethylamine suggest that bioaccumulation in aquatic organsms
would not be significant (HSDB 1998).
|
| |
| EC50 values to algae, mg/l : |
| 98.8 |
72 hr, Scenedesmus subspicatus |
| 74.2 |
96 hr, Scenedesmus subspicatus |
| |
IUCLID 1996 |
| |
| EC50 values to crustaceans, mg/l : |
| 165 |
24 hr, Daphnia magna Straus |
| 139 |
48 hr, Daphnia magna Straus |
| |
IUCLID 1996 |
| |
| LC50 values to fishes, mg/l : |
| 1000 |
48 hr, Oryzias latipes, IUCLID 1996 |
| |
-- |
| 1000 |
24 hr, Oryzias latipes |
| 1000 |
48 hr, Oryzias latipes |
| |
AQUIRE 2001 |
References |
| 1848 | Anon. 1987a.
The list of the existing chemical substances tested
on biodegradability by microorganisms or bioaccumulation in
fish body by Chemicals Inspection & Testing Institute.
Ministry
of International Trade and Industry, MITI.
Japan. |
| 3107 | AQUIRE 1993 -.
Aquatic Toxity Information Retrieval Database.
U.S.Environmental Protection Agency, Office of Pesticides and
Toxic Substances, Washington, D.C.
|
| 3338 | HAZARDTEXT Database. 1998 -.
Hazardous Materials Emergency
Response Information.
American Association of Railroads,
National Fire Protection Association, Department of
Transportation, Environmental Protection Agency and
Occupational Safely & Health Administration.
TOMES Plus CD-ROM.
|
| 3114 | HSDB Database 1992 -.
Hazardous Substances Data Bank.
US.
National Library of Medicine.
TOMES Plus CD-ROM.
|
| 3253 | IUCLID 1995 -.
International Uniform Chemical Information
Database.
European Commission.
European Chemicals Bureau.
Existing Chemicals.
Ispra, Italy.
|
| 3182 | LOG KOW 1994.
Octanol-water partition coefficient program.
Syracure Research Corporation.
Chemical Hazard Assessment
Division.
Environmental Chemistry Center.
|
| 3105 | MITI 1992.
Biodegradation and bioaccumulation data of existing
chemicals based on the CSCL Japan.
Compild under the Safety
Division Basic Industries Bureau Ministry of International
Trade & Industry, Japan.
Edited by Chemicals Inspection &
Testing Institute, Japan.
|
| 3340 | OVA 1999.
The safety instructions for some hazardous chemicals.
(available in Finnish)/Onnettomuuden vaaraa aiheuttavat
aineet -turvallisuusohjeet (OVA-ohjeet).
Työterveyslaitos
(Finnish Institute of Occupational Health),Työsuojelurahasto
(The Finnish Work Environment Fund).
Helsinki.
Finland.
|
