| Chemical |
Sodium fluoride |
| CAS-number : |
7681-49-4 |
| |
| Synonyms : |
| Natriumfluoridi |
| Sodium fluoride (NaF) |
| |
| Sumformula of the chemical : |
| NaF |
| EINECS-number : |
| 2316678 |
| |
| Uses : |
NF is used mostly as an additive e.g. in tooth pastes and
medicines.
|
| |
| Water solubility, mg/l : |
| 42000 |
10 °C |
| |
| Melting point, °C : |
| 992 |
|
| |
| Boiling point, °C : |
| 1704 |
|
| |
| LD50 values to mammals in non-oral exposure , mg/kg : |
| 10 |
24hr, ipr-small rodents |
| |
Hodge & Smith 1965 |
| |
| Other information of mammals : |
Tolerance limit for chronic injuries in mammals:
cattle, annual average: 30 - 50 mg/kg dry weight as NaF in food
(Eagers 1969).
|
| |
| LD50 values to birds in oral exposure, mg/kg : |
| 200 |
>200, orl-Sturnus vulgaris |
| |
Schafer et al. 1983 |
| |
| Effects on microorganisms : |
Toxicity threshold (cell multiplication inhibition test):
bacteria (Pseudomonas putida): 231 mg/l
(Bringmann & Kühn 1980a)
|
| |
| LC50 values to algae, mg/l : |
| 43 |
96hr, rpd, Scenedesmus |
| |
McKee & Wolf 1963 |
| |
| LC50 values to crustaceans, mg/l : |
| 340 |
48hr, Daphnia magna, LeBlanc 1980 |
| |
-- |
| 300 |
NaF, 48hr, shrimp, Sax 1986 |
| |
| EC50 values to crustaceans, mg/l : |
| 98 |
F-, 48hr, Daphnia, Dave 1984 |
| |
| Effects on physiology of water organisms : |
Indonaia caerulea, biochemical, oxygen consumption and other
physiological effects, 0.04 - 0.50 days, 0.5 mg/l (Mane et al.
1987).
|
| |
| Other information of water organisms : |
4.5 mg/l NaF, lobster, not toxic;
7.2 mg/l NaF, 108 hr, brown mussels, toxic effect;
52 mg/l, 72 d, mullet, crab, physical deterioration;
52 mg/l NaF, 72 d, shrimp, affects reproduction (Sax 1986).
Toxicity threshold (cell multiplication inhibition test):
green algae (Scenedesmus quadricauda): 249 mg/l
protozoa (Entosiphon sulcatum): 101 mg/l
(Bringmann & Kühn 1980a)
|
References |
| 2285 | Anon. 1989.
Miljöfarliga ämnen - exempellista och vetenskaplig
dokumentation. 303 p.
Stockholm.
Rapport från
kemikalieinspektionen (KEMI) 10. |
| 188 | Bringmann, G. & Kühn, R. 1980a.
Comparison of the toxicity
thresholds of water pollutants to bacteria, algae and
protozoa in the cell multiplication inhibition test.
Water
Res. 14: 231 - 241. |
| 312 | Dave, G. 1984b.
Effects of fluoride on growth, reproduction and
survival in Daphnia magna.
Comp.
Biochem.
Physiol. 78C(2):
425 - 431. |
| 2701 | Eagers, R.Y. 1969.
Toxic properties of inorganic fluorine
compounds.
Elsevier Publishing Company Ltd. |
| 2699 | Hodge, H.C. & Smith, F.A. 1965.
Fluorine Chemistry, Vol.
IV.
Academic Press Inc., New York and London. |
| 798 | LeBlanc, G.A. 1980.
Acute toxicity of priority pollutants
to water flea (Daphnia magna).
Bull.
Environm.
Contam.
Toxicol. 24: 684 - 691. |
| 2704 | Mane, U.H. et al. 1987.
Changes in metabolites and
physiological activities in a freshwater mussel, Indonaia
caeruleus (Prashad) due to short-term exposure to fluoride.
Fluoride 20: 84. |
| 921 | McKee, J.W. & Wolf, H.W. 1963.
Water quality criteria.
The
Resources Agency of California, State Water Quality Control
Board. |
| 2147 | Sax, I. 1986.
Hazardous chemicals information annual No. 1.
Van
Nostrand Reinhold Information Services, New York. 766 s. |
| 1743 | Schafer , E.W.Jr., Bowles, W.A.Jr., Hurlbut, J. 1983.
The acute
oral toxicity, repellency and hazard potential of 993 chemicals to
one or more species of wild and domestic birds.
Arch.
Environ.
Contam.
Toxicol. 12: 355 - 382. |
