Data bank of environmental chemicals     |     The Finnish Environment Institute (SYKE)


Data bank of environmental properties of chemicals

Sodium fluoride
CAS-number :
Synonyms :
Sodium fluoride (NaF)
Sumformula of the chemical :
EINECS-number :
Uses :
NF is used mostly as an additive e.g. in tooth pastes and
Water solubility, mg/l :
42000  10 °C
Melting point, °C :
Boiling point, °C :
LD50 values to mammals in non-oral exposure , mg/kg :
10  24hr, ipr-small rodents
  Hodge & Smith 1965
Other information of mammals :
Tolerance limit for chronic injuries in mammals:
cattle, annual average: 30 - 50 mg/kg dry weight as NaF in food
(Eagers 1969).
LD50 values to birds in oral exposure, mg/kg :
200  >200, orl-Sturnus vulgaris
  Schafer et al. 1983
Effects on microorganisms :
Toxicity threshold (cell multiplication inhibition test):
bacteria (Pseudomonas putida): 231 mg/l
(Bringmann & Kühn 1980a)
LC50 values to algae, mg/l :
43  96hr, rpd, Scenedesmus
  McKee & Wolf 1963
LC50 values to crustaceans, mg/l :
340  48hr, Daphnia magna, LeBlanc 1980
300  NaF, 48hr, shrimp, Sax 1986
EC50 values to crustaceans, mg/l :
98  F-, 48hr, Daphnia, Dave 1984
Effects on physiology of water organisms :
Indonaia caerulea, biochemical, oxygen consumption and other
physiological effects, 0.04 - 0.50 days, 0.5 mg/l (Mane et al.
Other information of water organisms :
4.5 mg/l NaF, lobster, not toxic;
7.2 mg/l NaF, 108 hr, brown mussels, toxic effect;
52 mg/l, 72 d, mullet, crab, physical deterioration;
52 mg/l NaF, 72 d, shrimp, affects reproduction (Sax 1986).

Toxicity threshold (cell multiplication inhibition test):
green algae (Scenedesmus quadricauda): 249 mg/l
protozoa (Entosiphon sulcatum): 101 mg/l
(Bringmann & Kühn 1980a)

2285Anon. 1989. Miljöfarliga ämnen - exempellista och vetenskaplig dokumentation. 303 p. Stockholm. Rapport från kemikalieinspektionen (KEMI) 10.
188Bringmann, G. & Kühn, R. 1980a. Comparison of the toxicity thresholds of water pollutants to bacteria, algae and protozoa in the cell multiplication inhibition test. Water Res. 14: 231 - 241.
312Dave, G. 1984b. Effects of fluoride on growth, reproduction and survival in Daphnia magna. Comp. Biochem. Physiol. 78C(2): 425 - 431.
2701Eagers, R.Y. 1969. Toxic properties of inorganic fluorine compounds. Elsevier Publishing Company Ltd.
2699Hodge, H.C. & Smith, F.A. 1965. Fluorine Chemistry, Vol. IV. Academic Press Inc., New York and London.
798LeBlanc, G.A. 1980. Acute toxicity of priority pollutants to water flea (Daphnia magna). Bull. Environm. Contam. Toxicol. 24: 684 - 691.
2704Mane, U.H. et al. 1987. Changes in metabolites and physiological activities in a freshwater mussel, Indonaia caeruleus (Prashad) due to short-term exposure to fluoride. Fluoride 20: 84.
921McKee, J.W. & Wolf, H.W. 1963. Water quality criteria. The Resources Agency of California, State Water Quality Control Board.
2147Sax, I. 1986. Hazardous chemicals information annual No. 1. Van Nostrand Reinhold Information Services, New York. 766 s.
1743Schafer , E.W.Jr., Bowles, W.A.Jr., Hurlbut, J. 1983. The acute oral toxicity, repellency and hazard potential of 993 chemicals to one or more species of wild and domestic birds. Arch. Environ. Contam. Toxicol. 12: 355 - 382.

© Copyright Environmental Administration