| Chemical |
Captan |
| CAS-number : |
133-06-2 |
| |
| Synonyms : |
| 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2- [(trichloromethyl)thio]- |
| 3a,4,7,7a-tetrahydro-N-(trikloorimetaanisulfenyyli)ftaalimidi |
| cis-N-((trichloromethyl)thio)-4-cyclohexene-1,2-dicarboximide. |
| kaptaani |
| N-((trichloromethyl)thio)-4-cyclohexene-1,2-dicarboximide |
| N-trichloromethylthiotetrahydrophthalimide |
| |
| Sumformula of the chemical : |
| C9H8Cl3NO2S |
| EINECS-number : |
| 2050870 |
| |
| Uses : |
Protectant-eradicant fungicide.
|
| |
| State and appearance : |
White solid.
|
| |
| Molecular weight : |
300.59 |
| |
| Water solubility, mg/l : |
| 0.5 |
< 0.5, 20°C |
| |
| Melting point, °C : |
| 175 |
|
| |
| Log octanol/water coefficient, log Pow : |
| 2.35 |
|
| |
| Photochemical degradation in air : |
Photooxidation half-life air:
32hr - 3.2hr, scientific judgement based upon an estimated rate
constant for the vapor phase reaction with hydroxyl radicals in
air (Howard 1991).
|
| |
| Hydrolysis in water : |
First-order hydrolysis half-life:
1.8hr, scientific judgement based upon first order rate
constant (6.5X10-3 s-1) at pH 7.1 and 28 °C (Howard 1991).
|
| |
| Hydrolysis in acid : |
Acid rate constant (M(H+)-hr)-1:
1.87X10-5 s-1, (t1/2 = 10.3hr) based upon first order rate
constant at pH 5.2 and 28 °C (Howard 1991).
|
| |
| Hydrolysis in base : |
Base rate constant (M(OH-)-hr)-1:
1.1X10-3 s-1, (t1/2 = 10.5min) based upon first order rate
constant at pH 8.3 and 28 °C (Howard 1991).
|
| |
| Half-life in air, days : |
| 1.33 |
32hr . 3.2, |
| 0.13 |
scientific judgement based upon estimated photooxidation half-life in air. |
| |
Howard 1991 |
| |
| Half-life in soil, days : |
| 3 |
Li et al. 1990 |
| |
-- |
| 60 |
60d - 2d, |
| 2 |
scientific judgement based upon unacclimated and acclimated soil grab sample data. |
| |
Howard 1991 |
| |
| Half-life in water, days : |
| 0.43 |
10.3hr - 10.5min, |
| 0.0073 |
in surface water: scientific judgement based upon aqueous hydrolysis half-lives for pH 5.2 (high t1/2) and 8.3 (low t1/2) at 28 °C. |
| 0.43 |
10.3hr - 10.5min, |
| 0.0073 |
in ground water: scientific judgement based upon aqueous hydrolysis half-lives for pH 5.2 (high t1/2) and 8.3 (low t1/2) at 28 °C. |
| |
Howard 1991 |
| |
| Aerobic degradation in water : |
Aerobic half-life:
60d - 2d, scientific judgement based upon unacclimated and
acclimated soil grab sample data (Howard 1991).
|
| |
| Anaerobic degradation in water : |
Anaerobic half-life:
240d - 8d, scientific judgement based upon unacclimated aerobic
biodegradation half-life (Howard 1991).
|
| |
| LD50 values to mammals in oral exposure, mg/kg : |
| 9000 |
orl-rat, Anon. 1976 |
| 740 |
orl-rbt, Lewis & Sweet 1984 |
| |
| Other information of mammals : |
In diet: no effect level from 2 years dietary tests on rats;
1000 mg/kg (Martin 1968).
|
| |
| Carcinogenicity : |
Carcinogenic (McCann et al. 1975).
NCI carcinogenesis bioassay completed: results positive, mus;
results negative, rat (Lewis & Sweet 1984).
|
| |
| Mutagenicity : |
Mutagenicity in the Salmonella test positive (without liver
homogenate):
25 revertant colonies/nmol;
820 revertant colonies at 0.010 mg/plate
(McCann et al. 1975).
|
| |
| LD50 values to birds in oral exposure, mg/kg : |
| 100 |
100 - 104, orl-Agelaius phoeniceus |
| 104 |
|
| 100 |
>100, orl-Passer domesticus |
| 100 |
>100, orl-Quiscalus quiscula |
| 100 |
>100, orl-Corvus brachyrhynchos |
| |
Schafer et al. 1983 |
| |
| Effects on plants : |
Development of mycorrhizal fungi in roots of sour orange
(Citrus aurantium) seedlings was reduced by spraying of soil
with 9.0 kg captan (50 %) /ha (Nemec 1980).
|
| |
| LC50 values to crustaceans, mg/l : |
| 1.5 |
srv,act, Daphnia pulex, Hashimoto & |
| |
Nishiuchi 1981 |
| |
| LC50 values to fishes, mg/l : |
| 0.04 |
srv,act, 48 hr, Carassius auratus, |
| 0.25 |
srv,act, 48 hr, Cyprinus carpio, |
| |
Hashimoto & Nishiuchi 1981 |
| |
-- |
| 0.3 |
srv,act, 96 hr, Rasbora heteromorpha, |
| |
Tooby et al. 1975 |
| |
| LOEC values to fishes, mg/l : |
| 0.04 |
srv,chr, Pimephales promelas, |
| |
Hermanutz et al. 1973 |
| |
| NOEC values to fishes, mg/l : |
| 0.017 |
rpd,grw, Pimephales promelas, |
| |
Hermanutz et al. 1973 |
References |
| 63 | Anon. 1976.
Pesticide Dictionary 1976.
Farm Chemicals, Meister
Publishing Company, 37841 Euclid Avenue, Willoughby, Ohio
44094. |
| 550 | Hashimoto, Y. & Nishiuchi Y. 1981.
Establishment of
bioassay methods for the evaluation of acute toxicity of
pesticides to aquatic organisms.
J.
Pestic.
Sci.
(Jap.) 6: 257. |
| 3120 | Howard, P.H., Boethling, R.S., Jarvis, W.F., Meylan, W.M. &
Michalenko, E.M., Handbook of Environmental Degradation Rates,
1991.
Lewis Publicers, Inc., Chelsea, Michigan, U.S.A.,
pp. 725.
|
| 1589 | Lewis, R.J. & Sweet, D.V. 1984.
Registry of toxic effects of
chemical substances.
National Institute for Occupational Safety
and Health.
No. 83-107-4. |
| 2450 | Li, W.,Merrill, D.
E. & Haith, A. 1990.
Loading functions for
pesticide runoff.
Research Journal WPCF, 62(1): pp. 16 - 26. |
| 897 | Martin, H. 1968.
Pesticide manual, British crop protection
council, Clacks Farm, Boreley, Ombersley, Droitwich, Worcester,
U.K. |
| 912 | McCann, J. et al. 1975.
Detection of carcinogens as
mutagens in the Salmonella/microsome test: Assay of 300
chemicals, Proc.
Nat.
Acad.
Sci.
USA, 72(12): 5135-5139 Medical
Sciences, Dec. |
| 1726 | Nemec, S. 1980.
Effects of 11 fungicides on endomycorrhizal
development in sour orange.
Can.
J.
Bot. 58(5): 522 - 526. |
| 1743 | Schafer , E.W.Jr., Bowles, W.A.Jr., Hurlbut, J. 1983.
The acute
oral toxicity, repellency and hazard potential of 993 chemicals to
one or more species of wild and domestic birds.
Arch.
Environ.
Contam.
Toxicol. 12: 355 - 382. |
| 1427 | Tooby, T.E., Hursey, P.A. & Alabaster, J.S. 1975: The acute
toxicity of 102 pesticides and miscellaneous substances to
fish.
Chemistry and Industry 21: 523-525. |
| 1468 | Verschueren, K. 1983.
Handbook of environmental data of
organic chemicals.
Van Nostrand Reinhold Co.
Inc., New York.
1310 s. |
