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Data bank of environmental chemicals     |     The Finnish Environment Institute (SYKE)
 


24.4.2024

Data bank of environmental properties of chemicals


Chemical
2-Aminopyridine
CAS-number :
504-29-0
 
Synonyms :
2-aminopyridiini
2-Pyridinamine
alpha-pyridylamine
 
Sumformula of the chemical :
C5H6N2
EINECS-number :
2079884
 
Molecular weight :
94.11
 
Vapor density (air=1) :
3.25 
 
Conversion factor, 1 ppm in air=_mg/m3 :
3.91  mg/m3
 
Conversion factor, 1 mg/m3 in air=_ppm :
0.26  ppm
 
Water solubility, mg/l :
4000  >4000, MITI 1992
 
Melting point, °C :
56 
61  MITI 1992
 
Boiling point, °C :
204 
204  MITI 1992
 
Log octanol/water coefficient, log Pow :
-0.22 
0.6  MITI 1992
 
Total degradation in water :
Biodegradation:
0% by BOD
period: 28d
substance: 100 mg/l
sludge: 30 mg/l
(MITI 1992)
 
Bioconcentration factor, fishes :
3.0 - 7.7, 6w, Cyprinus carpio, conc 0.1 mg/l,
7.7 
5.1  < 5.1 - 25, 6w, Cyprinus carpio, conc 0.01 mg/l,
25  MITI 1992
 
Other information of bioaccumulation :
Confirmed to be non-accumulative or low accumulative (Anon.
1987).
 
LD50 values to mammals in oral exposure, mg/kg :
200  orl-rat, Patty 1967
50  orl-mus
 
Health effects :
Man: readily absorbed through the skin
     transient symptoms: 5.2 ppm, 8 hours (Patty 1967).
 
LD50 values to birds in oral exposure, mg/kg :
31.6  orl-Agelaius phoeniceus
75  75.0 - 100, orl-Sturnus vulgaris
100 
133  orl-Coturnix coturnix
75  orl-Passer domesticus
  Schafer et al. 1983
 
LC50 values to fishes, mg/l :
10  48hr, Oryzias latipes, MITI 1992
 
Other information of water organisms :
EC50, 60hr, 390 mg/l, rpd, Tetrahymena pyriformis (Schultz &
Applehans 1985).

EC50, 2.5 days, 393 mg/l, grw, Tetrahymena pyriformis (Schultz et
al. 1987).

References
1848Anon. 1987a. The list of the existing chemical substances tested on biodegradability by microorganisms or bioaccumulation in fish body by Chemicals Inspection & Testing Institute. Ministry of International Trade and Industry, MITI. Japan.
3105MITI 1992. Biodegradation and bioaccumulation data of existing chemicals based on the CSCL Japan. Compild under the Safety Division Basic Industries Bureau Ministry of International Trade & Industry, Japan. Edited by Chemicals Inspection & Testing Institute, Japan.
1644Patty, F.A. 1967. Industrial hygiene and toxicology. Vol 2. Interscience Publishers.
1743Schafer , E.W.Jr., Bowles, W.A.Jr., Hurlbut, J. 1983. The acute oral toxicity, repellency and hazard potential of 993 chemicals to one or more species of wild and domestic birds. Arch. Environ. Contam. Toxicol. 12: 355 - 382.
1906Schultz, T.W. et al. 1987. Structure-activity relationships of selected pyridines. III Log Kow analysis. Ecotoxical. Environ. Saf. 13: 76.
1248Shultz, T.W. & Applehans, F.M. 1985. Correlations for the acute toxicity of multiple nitrogen substituted aromatic molecules. Ecotox. Environm. Safety 10: 75 - 85.
1468Verschueren, K. 1983. Handbook of environmental data of organic chemicals. Van Nostrand Reinhold Co. Inc., New York. 1310 s.

 
 
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