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Data bank of environmental chemicals     |     The Finnish Environment Institute (SYKE)
 


29.3.2024

Data bank of environmental properties of chemicals


Chemical
Thiophanate-methyl
CAS-number :
23564-05-8
 
Synonyms :
dimethyl-4,4'-(o-phenylene)bis(3-thioallophanate)
tiofanaattimetyyli
 
Sumformula of the chemical :
C14H18N4O4S2
 
Uses :
Active ingredient in fungicides.
 
Molecular weight :
342.42
 
LD50 values to mammals in oral exposure, mg/kg :
6640  orl-rat, Lewis & Sweet 1984
3400  orl-mus, - " -
2270  orl-rbt, - " -
3640  orl-gpg, - " -
 
LD50 values to mammals in non-oral exposure , mg/kg :
1140  ipr-rat, Lewis & Sweet 1984
790  ipr-mus, Lewis & Sweet 1984
 
LDLo values to mammals in oral exposure, mg/kg :
4000  orl-dog, Lewis & Sweet 1984
 
LD50 values to birds in oral exposure, mg/kg :
50000  > 50000, orl-japonese qal, Verschueren
  1983
 
Effects on plants :
Topsin-M was applied to soil using 70 % a.i. wettable powder:
0.026 grams of Topsin-M available per plant caused decrease in
chloroplast activity of the leaves of gherkin seedlings
(van Wambeke et al. 1977).
 
LC50 values to algae, mg/l :
8.5  48 hr, Chlorella pyrenoidesa, Canton
  1976
 
LC50 values to crustaceans, mg/l :
16  48 hr, Daphnia magna, Canton 1976
 
LC50 values to fishes, mg/l :
7.8  48 hr, Salmo gairdneri, Canton 1976
  --
11  48 hr, Cyprinus carpio
  Pesticide Manual 1983

References
70Anon. 1983c. Pesticide Manual. Worthing, C.R. (toim.) A world compedium. The British Crop Biotection Council. London. 7 th edition.
239Canton, J.H. 1976. The toxicity of benomyl, thiophnate-methyl, and BCM to four freshwater organisms. Bull. Environ. Contam. Toxicol. 16(2): 214 - 218.
1589Lewis, R.J. & Sweet, D.V. 1984. Registry of toxic effects of chemical substances. National Institute for Occupational Safety and Health. No. 83-107-4.
1600van Wambeke, E., á Campo, P. & Vanachter, A. 1977. Influence of MBC on some physiological processes in the leaves of gherkin. Neth. J. Pl. Path. 83(1): 411 - 416.
1468Verschueren, K. 1983. Handbook of environmental data of organic chemicals. Van Nostrand Reinhold Co. Inc., New York. 1310 s.

 
 
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