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Data bank of environmental chemicals     |     The Finnish Environment Institute (SYKE)
 


25.4.2024

Data bank of environmental properties of chemicals


Chemical
2-chloro-N,N-diethyl-3-hydroxycrotonamide, dimethyl phosphate
CAS-number :
13171-21-6
 
Synonyms :
1-chloro-diethylcarbamoyl-1-propen-2-yl dimethyl phosphate
dimecron
dimethyl 2-chloro-2-diethylcarbamoyl-1-methylvinylphosphate
famfos
fosfamidon
O,O-dimethyl-O-(2-chloro-2-(N,N-diethylcarbamoyl)-1-methylvinyl phosphate
phosphamidon
Phosphoric acid, dimethyl ester, ester with2-chloro-N,N-diethyl-3-hydroxycrotonamide
 
Sumformula of the chemical :
C10H19ClNO5P
 
Uses :
insecticide, acaricide
 
Molecular weight :
299.72
 
LD50 values to mammals in oral exposure, mg/kg :
15  orl-rat, Lewis & Sweet 1984
17  orl-rat
orl-mus
9.04  orl-ckn
3.81  orl-dck
orl-bwd
 
LD50 values to mammals in non-oral exposure , mg/kg :
125  skn-rat, Lewis & Sweet 1984
26  scu-rat
ivn-mus
267  skn-rbt
26  skn-dck
 
LC50 values to mammals in inhalation exposure, mg/m3 :
135  ihl-rat, Lewis & Sweet 1984
 
TDLo values to mammals in oral exposure, mg/kg :
5400  orl-rat, Lewis & Sweet 1984
 
Other information of mammals :
ALD = 18 mg/kg, act, orl, deer mouse;
LDfr = 50 mg/kg/day, subacute, deer mouse (Virtanen & Nuuja
1987).
 
Carcinogenicity :
NCI carcinogenesis bioassay completed: results indefinite, rat;
results negative, mus (Lewis & Sweet 1984).
 
LD50 values to birds in oral exposure, mg/kg :
orl-bwd, Lewis & Sweet 1984
3.81  orl-dck, - " -
 
LD50 values to birds in dermal exposure, mg/kg :
26  skn-dck, Lewis & Sweet 1984
 
LC50 values to crustaceans, mg/l :
0.0088  srv,act, 48 hr, Daphnia pulex, Sanders &
  Cope 1966
0.0028  srv,act, 96 hr, Gammarus lacustris,
  Sanders 1969
1.63  rpd,act, 48 hr, Macrobrachium lamerrei,
  Nagabhushanam et al. 1983
0.0125  srv,act, Daphnia magna, Kenaga 1979
 
LC50 values to fishes, mg/l :
srv,act, 24 hr, Salmo gairdneri, Edwards
  1977
4.5  srv,act, 96 hr, Lepomis macrohirus,
  Verschueren 1983
10.5  srv,act, 96 hr, Channa striata,
  Choudhuri et al. 1984
srv,act, Salmo gairdneri, Kenaga 1979

References
377Edwards, C.A. 1977. Nature and origins of pollution of aquatic systems by pesticides. In: Pesticides in Aquatic Environments. M.A. Q. Khan, (ed.) Plenum Press, N.Y.
1589Lewis, R.J. & Sweet, D.V. 1984. Registry of toxic effects of chemical substances. National Institute for Occupational Safety and Health. No. 83-107-4.
1225Sanders, H.O. & Cope, O.B. 1966. Toxicities of several pesticides to two species of cladocerans. Trans. Am. Fish Soc. 95: 165 - 169.
1221Sanders, H.O. 1969. Toxicity of pesticides to the Crustacean, Gammarus lacustris. Bureau of Sport Fisheries and Wildlife technical paper 25, Government Printing Office, Washington, D.C.
1468Verschueren, K. 1983. Handbook of environmental data of organic chemicals. Van Nostrand Reinhold Co. Inc., New York. 1310 s.
1771Virtanen, M. & Nuuja, I. 1987. Kemikaalien myrkyllisyys luonnonvaraisille nisäkkäille. Ympäristöministeriö. Ympäristön- ja luonnonsuojeluosasto. Sarja D: 26.

 
 
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