| Chemical |
Isopropanol |
| CAS-number : |
67-63-0 |
| |
| Synonyms : |
| 2-propanol |
| 2-propanoli |
| dimethylcarbinol |
| Isopropanoli |
| isopropyl alcoho |
| propan-2-ol |
| sec-propyl alcohol |
| |
| Sumformula of the chemical : |
| C3H8O |
| EINECS-number : |
| 2006617 |
| |
| Uses : |
Solvent.
|
| |
| Odor : |
Quality: sharp, musty
Hedonic tone: unpleasant
Threshold odour concentration
absolute: 3.20 ppm
50 % recognition: 7.50 ppm
100 % recognition: 28.2 ppm
Odour index 100 % recognition: 1 539
(Hellman & Small 1974)
|
| |
| Molecular weight : |
60.11 |
| |
| Conversion factor, 1 ppm in air=_mg/m3 : |
| 2.5 |
mg/m3, Verschueren 1983 |
| |
| Conversion factor, 1 mg/m3 in air=_ppm : |
| 0.408 |
ppm, Verschueren 1983 |
| |
| Boiling point, °C : |
| 82.5 |
|
| |
| Log octanol/water coefficient, log Pow : |
| 0.05 |
Sangster 1989 |
| |
| Henry's law constant, Pa x m3/mol : |
| 1.131 |
calc. Yaws et al. 1991 |
| |
| Volatilization : |
Relative volatility (nBuAc=1) = 2.30
|
| |
| Photochemical degradation in air : |
Photooxidation half-life in air:
6.2hr - 72hr,
based upon measured rates for reaction with hydroxyl radicals in
air (Howard 1991).
|
| |
| Photochemical degradation in water : |
Photooxidation half-life in water:
197d - 22yr,
based upon measured rates for reaction with hydroxyl radicals in
water (Howard 1991)
|
| |
| Chemical oxygen demand, g O2/g : |
| 2.23 |
5 days, Bridie et al. 1979 |
| |
| Biochemical oxygen demand, g O2/g : |
| 1.19 |
5 days, Bridie et al. 1979 |
| |
| Half-life in air, days : |
| 0.26 |
6.2hr - 73hr, |
| 3 |
based upon photooxidation half-life in air, |
| |
Howard 1991 |
| |
| Half-life in soil, days : |
| 1 |
24hr - 168hr, |
| 7 |
scientific judgement based upon estimated |
| |
unacclimated aerobic aqueous biodegradation |
| |
half-life, |
| |
Howard 1991 |
| |
| Half-life in water, days : |
| 1 |
24hr - 168hr, |
| 7 |
in surface water, scientific judgement based upon |
| |
estimated unacclimated aerobic aqueous |
| |
biodegradation half-life, |
| 2 |
48hr - 336hr, |
| 14 |
in ground water, scientific judgement based upon |
| |
estimated unacclimated aerobic aqueous |
| |
biodegradation half-life, |
| |
Howard 1991 |
| |
| Aerobic degradation in water : |
Aerobic half-life:
24hr - 168hr,
scientific judgement based upon unacclimated aerobic aqueous
screening test data (Howard 1991)
|
| |
| Anaerobic degradation in water : |
Anaerobic half-life:
96hr - 672hr,
scientific judgement based upon estimated aqueous aerobic
biodegradation half-life and unacclimated anaerobic aqueous
screening test data (Howard 1991)
|
| |
| LD50 values to mammals in oral exposure, mg/kg : |
| 4797 |
orl-dog |
| 3600 |
orl-mus |
| 5045 |
orl-rat |
| |
Sweet 1987 |
| |
| LD50 values to mammals in non-oral exposure , mg/kg : |
| 2560 |
ipr-gpg |
| 3444 |
ipr-hms |
| 4477 |
ipr-mus |
| 2735 |
ipr-rat |
| 667 |
ipr-rbt |
| 1509 |
ivn-mus |
| 1088 |
ivn-rat |
| 1184 |
ivn-rbt |
| 12800 |
skn-rbt |
| |
Sweet 1987 |
| |
| LDLo values to mammals in oral exposure, mg/kg : |
| 3570 |
orl-hmn, Sweet 1987 |
| |
| LDLo values to mammals in non-oral exposure , mg/kg : |
| 1963 |
ivn-cat |
| 5120 |
ivn-dog |
| 6 |
scu-mam |
| 6000 |
scu-mus |
| |
Sweet 1987 |
| |
| LCLo values to mammals in inhalation exposure, ppm : |
| 12800 |
ihl-mus, 3hr |
| 12000 |
ihl-rat, 8hr |
| |
Sweet 1987 |
| |
| TDLo values to mammals in oral exposure, mg/kg : |
| 11340 |
orl-rat, 45d preg. |
| |
maternal effects |
| 5040 |
orl-rat, 1-20d preg. |
| |
effects on fertility |
| 20160 |
orl-rat, 1-20d preg. |
| |
effects on fertility |
| 6480 |
orl-rat, effects on newborn |
| 223 |
orl-hmn |
| 14432 |
orl-man |
| |
Sweet 1987 |
| |
| Effects on microorganisms : |
Toxicity threshold (cell multiplication inhibition test):
bacteria (Pseudomonas putida): 1050 mg/l
(Bringmann & Kühn 1980a)
|
| |
| EC50 values to microorganism, mg/l : |
| 30897 |
Biodegradation inhibition, |
| |
Vaishnav 1986 |
| |
| LOEC values to algae, mg/l : |
| 1000 |
rpd,schr, Microcystis aeruginosa, |
| |
Bringmann & Kühn 1976 |
| |
| LC50 values to fishes, mg/l : |
| 7060 |
7 d, Poelicia reticulata, |
| |
Könemann 1979 |
| |
-- |
| 10400 |
96 hr, Pimephales promelas, |
| |
Veith et al. 1983 |
| |
-- |
| 5000 |
> 5000, 24 hr, Carassius auratus |
| |
Bridie et al. 1982 |
| |
-- |
| 9640 |
96 hr, Pimephales promelas |
| 10400 |
96 hr, Pimephales promelas |
| 6550 |
96 hr, Pimephales promelas, Brooke et al. 1984 |
| |
| EC50 values to fishes, mg/l : |
| 9540 |
96 hr, mbt, Pimephales promelas |
| 9490 |
96 hr, mbt, Pimephales promelas |
| 6120 |
96 hr, mbt, Pimephales promelas, Brooke et al. 1984 |
| |
| Other information of water organisms : |
Toxicity threshold (cell multiplication inhibition test):
green algae (Scenedesmus quadricauda): 1800 mg/l
protozoa (Entosiphon sulcatum): 4930 mg/l
(Bringmann & Kühn 1980a)
|
References |
| 182 | Bridie, A.L. et al. 1979.
The acute toxicity of some
petrochemicals to goldfish.
Water Res. 13: 623. |
| 1680 | Bridie, A.L., Wolff, C.J.M. & Winter, M. 1979.
BOD and COD of
some petrochemicals.
Water Res. 13: 627 - 630. |
| 187 | Bringmann, G. & Kühn, R. 1976.
Vergleichende Befunde der
Schadwirkung wassergefährdender Stoffe gegen Bakterien
(Pseudomonas putida) und Blaualgen (Microcystis aeruginosa).
Gwf-Wasser-Abwasser 117(9). |
| 188 | Bringmann, G. & Kühn, R. 1980a.
Comparison of the toxicity
thresholds of water pollutants to bacteria, algae and
protozoa in the cell multiplication inhibition test.
Water
Res. 14: 231 - 241. |
| 3295 | Brooke, L.
T. et al. 1984.
Acute toxicities of organic
chemicals to fathead minnows (Pimephales promelas); Vol 1.
Center for Lake Superior Environmental Studies University of
Wisconsin-Superior, Superior, Wisconsin, U.S.A.
|
| 1673 | Hellman, T.M. & Small, F.H. 1974.
Characterization of the odour
properties of 101 petrochemicals using sensory methods.
J.
Air
Pollut.
Control Assoc. 24: 979 - 982. |
| 3120 | Howard, P.H., Boethling, R.S., Jarvis, W.F., Meylan, W.M. &
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1991.
Lewis Publicers, Inc., Chelsea, Michigan, U.S.A.,
pp. 725.
|
| 761 | Könemann, W.H. 1979.
Quantitative structure-activity
relationships for kinetics and toxicity of aquatic pollutants and
their mixtures in fish.
Univ.
Utrecht, Netherlands. |
| 3104 | Sangster, J. 1989.
Octanol-water partition coefficients of
simple organic compounds.
J.
Phys.
Chem.
Ref.
Data, Vol 18, No.
3: 1111 - 1229. |
| 2101 | Sweet, D. 1987.
Registry of toxic effects of chemical
substances 1985 - 1986 edition.
U.S.
Department of health and
human services. |
| 2416 | Vaishnav, D.
D. 1986.
Chemical structure-biodegradation
inhibition and fish acute toxicity relationships for narcotic
industri chemicals.
Toxicity Assessment 1: 227. |
| 1456 | Veith, G.D. et al. 1983.
Estimating the acute toxicity of
narcotic industrial chemicals to fathead minnows.
In:
Aquatic toxicology and hazard assessment: sixth symposium.
ASTM STP 803.
Bishop, W.E. et al.
(eds.).
Am.
Soc.
Test.
Mater, Philadelphia, Pa, 90. |
| 1468 | Verschueren, K. 1983.
Handbook of environmental data of
organic chemicals.
Van Nostrand Reinhold Co.
Inc., New York.
1310 s. |
| 2413 | Walker, J.
D. 1987.
Effects of chemicals on microorganisms.
Journal WPCF 59 (6): 614 - 625. |
| 3030 | Yaws, C., Yang, H-C. & Pan, X. 1991.
Henry's law constants for
362 organic compounds in water.
Chemical Engineering.
November.
p 179 - 185. |
