| Chemical |
O,O-dimethyl S-(2(methylamino)-2-oxoethyl) phosphorodithioate |
| CAS-number : |
60-51-5 |
| |
| Synonyms : |
| acetic acid,O,O-dimethyldithiophosphoryl-, N-monomethylamide salt |
| dimethoate |
| Dimetoaatti |
| dimeton |
| fosfamid |
| fosfotox |
| O,O-dimethyl-S-(N-methylcarbamoyl)-methyl)phosphorodithioate |
| O,O-dimethyl-S-(N-methylcarbamoylmethyl) dithiophosphate |
| O,O-dimethyldithiophosphoryl acetic acid, N-monomethylamidesalt |
| phosphamid |
| phosphamide |
| phosphorodithioic acid, O,O-dimethylester,s-ester with 2-mercapto-N-methylacetamide. |
| rogor |
| trimetion |
| |
| Sumformula of the chemical : |
| C5H12NO3PS2 |
| EINECS-number : |
| 2004803 |
| |
| Uses : |
Acaricide, active ingredient in insecticides.
|
| |
| Molecular weight : |
229.27 |
| |
| Vapor pressure, mmHg : |
| 0.0000083 |
at 25°C, KEMI 1991 |
| 0.0000051 |
at 25°C, Howard Vol III 1991 |
| |
| Water solubility, mg/l : |
| 25000 |
room.temp. |
| 25000 |
at 21°C, KEMI 1991 |
| 10000 |
>10000, MITI 1992 |
| |
| Melting point, °C : |
| 51 |
51 - 52 °C, KEMI 1991 |
| 52 |
|
| 48 |
48-50, MITI 1992 |
| |
| Log octanol/water coefficient, log Pow : |
| 1.78 |
Anon 1988 |
| 0.7 |
KEMI 1991 |
| 0.79 |
MITI 1992 |
| |
-- |
| 0.28 |
LOGKOW 1994 |
| |
| Log soil sorption coefficient, log Kom : |
| 0.72 |
Sabljic 1987 |
| |
| Henry's law constant, Pa x m3/mol : |
| 0.00001 |
Anon 1988 |
| |
| Mobility : |
Equilibrium distribution:
mass %
air 0.00
water 99.08
solid 0.91
(Anon 1988)
The leaching behaviour of dimethionate was studied with soil
thin-layer plates and with soil columns.
According to the
studies dimethionate is very mobile;
Rf: 0.89 - 0.97 (sandy loam - loam)
Koc: 12 -35 (sandy soil - clay soil)
(KEMI 1991).
|
| |
| Photochemical degradation in air : |
Photooxidation half-life in air:
0.469hr - 4.69hr,
scientific judgement based upon estimated rate constant for
reaction with hydroxyl radicals in air (Howard 1991).
|
| |
| Hydrolysis in water : |
First-order hydrolysis half-life:
118d, based upon measured neutral and base catalyzed
hydrolysis rate constant (Howard 1991).
|
| |
| Hydrolysis in base : |
Base rate constant 756,
(t1/2 = 90.8hr (3.78d) at pH 9 and 25°C), based upon measured
neutral and base catalyzed hydrolysis rate constants
(Howard 1991).
|
| |
| Half-life in air, days : |
| 0.02 |
0.469hr - 4.69hr, |
| 0.2 |
scientific judgement based upon estimated |
| |
photooxidation half-life in air, |
| |
Howard 1991 |
| |
| Half-life in soil, days : |
| 11 |
11d - 37d, |
| 37 |
based upon soil die-away test data for two soils, |
| |
Howard 1991 |
| |
| Half-life in water, days : |
| 11 |
11d - 56d, in surface water, |
| 56 |
scientific judgement based upon estimated |
| |
unacclimated aqueous aerobic biodegradation |
| |
half-life, |
| 22 |
22d - 112d, in ground water, |
| 112 |
scientific judgement based upon estimated |
| |
unacclimated aqueous aerobic biodegradation |
| |
half-life, |
| |
Howard 1991 |
| |
| Aerobic degradation in soil : |
Dimethionate is degraded in soil by microorganisms.
Degradation
product at aerobic and anaerobic conditions is
O-desmethyl-dimethoate.
Half-life in aerobic degradation varies
from 3 - 42 days and 9 - 27% of C-14 applied radioactivity was
recovered after 6 months (KEMI 1991).
|
| |
| Aerobic degradation in water : |
Aerobic half-life:
11d - 56d,
based upon river die-away test data and soil die-away test data
(Howard 1991).
|
| |
| Anaerobic degradation in water : |
Anaerobic half-life:
44d - 224d,
scientific judgement based upon estimated
unacclimated aqueous aerobic biodegradation half-life
(Howard 1991).
|
| |
| Total degradation in water : |
50 % of original compound found after 8 weeks (river water,
initial conc. 0.010 mg/l) (Verschueren 1983).
Biodegradation:
0% by BOD
period: 28d
substance: 100 mg/l
sludge: 30 mg/l
(MITI 1992)
|
| |
| Bioconcentration factor, fishes : |
| 0.4 |
0.4 - 0.8, 6w, Cyprinus carpio, conc 2 mg/l, |
| 0.8 |
|
| 1.6 |
< 1.6, 6w, Cyprinus carpio, conc 0.2 mg/l, |
| |
| Other information of bioaccumulation : |
Confirmed to be non-accumulative or low accumulative
(O,O-dimethyl-S-(N-methyl carbamoyl methyl) dithiophosphate)
(Anon. 1987).
|
| |
| LD50 values to mammals in oral exposure, mg/kg : |
| 152 |
orl-rat, Lewis & Sweet 1984 |
| 60 |
orl-mus |
| 30 |
orl-hmn |
| 15 |
orl-mam |
| 400 |
orl-dog |
| |
| LD50 values to mammals in non-oral exposure , mg/kg : |
| 45 |
ipr-mus, Lewis & Sweet 1984 |
| 60 |
scu-mus |
| 353 |
skn-rat |
| 100 |
ipr-rat |
| 350 |
scu-rat |
| 450 |
ivn-rat |
| |
| LDLo values to mammals in oral exposure, mg/kg : |
| 300 |
orl-cat, Lewis & Sweet 1984 |
| |
| TDLo values to mammals in oral exposure, mg/kg : |
| 256 |
orl-rat, Lewis & Sweet 1984 |
| 120 |
orl-rat |
| |
| TDLo values to mammals in non-oral exposure , mg/kg : |
| 176 |
ims-rat, Lewis & Sweet 1984 |
| |
| Carcinogenicity : |
NCI carcinogenesis bioassay completed: results negative,
mus, rat (Lewis & Sweet 1984).
|
| |
| LD50 values to birds in oral exposure, mg/kg : |
| 22 |
orl-brd, Lewis & Sweet 1984 |
| 7 |
orl-bwd |
| 37 |
orl-ckn |
| |
-- |
| 6.6 |
6.6 - 17.8, orl-Agelaius phoenicus, |
| 17.8 |
|
| 31.6 |
orl-Sturnus vulgaris |
| |
Schafer et al. 1983 |
| |
| Effects on amphibia : |
LC50 0.008 mg/l, 96hr, tadpoles of Rana hexadactyla
(Khangarot et al. 1985).
NOEC, 1 mg/l, 100d, Xenopus laevis, mortality;
NOEC, 32 mg/l, 100d, Xenopus laevis, development;
NOEC, 32 mg/l, 100d, Xenopus laevis, growth;
(Slooff & Canton 1983).
|
| |
| Effects on anthropods : |
NOEC, 0.32 mg/l, 25d, Culex pipiens, mortality;
NOEC, 0.32 mg/l, 25d, Culex pipiens, development;
(Slooff & Canton 1983).
|
| |
| Effects on plants : |
NOEC, 32 mg/l, 7d, Lemna minor, specific growth rate (Slooff
& Canton 1983).
|
| |
| Effects on microorganisms : |
NOEC, 320 mg/l, 0,3d, Pseudomonas fluorescens, specific growth
rate.
NOEC, 32 mg/l, 4d, Microcystis aeruginosa, specific growth
rate (Slooff & Canton 1983).
|
| |
| NOEC values to algae, mg/l : |
| 32 |
96hr, grw, Microcystis aeruginosa |
| |
Slooff & Canton 1983 |
| |
-- |
| 100 |
4d, grw (biomass), Scendesmus |
| |
pannonicus, Slooff & Canton 1983 |
| |
| LC50 values to crustaceans, mg/l : |
| 0.01 |
Daphnia magna, Nishiuchi & Hashimoto |
| |
1967 |
| |
-- |
| 0.001 |
48 hr, Crangon crangon, Kemp et al. 1973 |
| |
-- |
| 4.57 |
96 hr, Saccobranchus fossilis, Verma et |
| |
al. 1982a |
| |
-- |
| 6.4 |
48 hr, Daphnia magna, Hermens et al.1984 |
| |
-- |
| 2.5 |
act, Daphnia magna, Kenaga 1979 |
| |
-- |
| 4.275 |
1d, Macrobrachium lamarrei |
| 2.63 |
3d, Macrobrachium lamarrei |
| |
Mary et al. 1986 |
| |
| EC50 values to crustaceans, mg/l : |
| 0.31 |
16 days, rpd, Daphnia magna |
| |
Hermens et al. 1984 |
| |
| NOEC values to crustaceans, mg/l : |
| 0.032 |
21 days, srv, Daphnia magna |
| |
Slooff & Canton 1983 |
| |
-- |
| 0.1 |
21d, rpd, Daphnia magna |
| |
Slooff & Canton 1983 |
| |
| LC50 values to fishes, mg/l : |
| 8.5 |
act, Salmo gairdneri, Kenaga 1979 |
| 6 |
act, Lepomis macrochirus |
| |
-- |
| 28 |
24hr, Poelicia reticulata, Edwards 1977 |
| 20 |
24hr, Salmo gairdneri |
| |
-- |
| 18.97 |
96hr, Poelicia reticulata |
| |
Gupta et al. 1984 |
| |
-- |
| 40 |
40 - 60, 96hr, Gambusia affinis |
| 60 |
Pesticide Manual 1983 |
| |
-- |
| 40 |
> 40, 48hr, Cyprinus carpio |
| |
Nishiuchi & Hashimoto 1967 |
| |
-- |
| 4.65 |
4d, Cyprinus carpio |
| |
Kulshrestha & Arora 1986 |
| |
-- |
| 840 |
48hr, Oryzias latipes, MITI 1992 |
| |
| NOEC values to fishes, mg/l : |
| 32 |
28d, srv, Poecilia reticulata |
| 0.1 |
28d, srv + bhv, Poecilia reticulata |
| 10 |
28d, grw, Poecilia reticulata |
| 0.32 |
40d, srv, Oryzias latipes |
| 0.32 |
40d, srv + bhv, Oryzias latipes |
| 100 |
40d, grw, Oryzias lapites |
| |
Slooff & Canton 1983 |
| |
| Effects on physiology of water organisms : |
Biochemical effect (change in physiochemical process including
glycogen uptake, cholesterol levels and lipid analysis):
0.41 mg/l, 35 d, Channa punctatus, Labeo rohita, Tilapia
mossambica (Ghosh 1987).
|
| |
| Other information of water organisms : |
NOEC, 100 mg/l, 21d, Hydra oligactis, specific growth rate;
NOEC, 32 mg/l, 40d, Lymnaea stagnalis, mortality;
NOEC, 10 mg/l, 40d, Lymnaea stagnalis, reproduction;
NOEC, 32 mg/l, 40d, Lymnaea stagnalis, hatching;
(Slooff & Canton 1983).
|
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